BDBM50662111 CHEMBL6133839

SMILES Nc1ccc2cc(C(=O)N(Cc3ccc(C(F)(F)F)cn3)Cc3ccccc3F)ccc2n1

InChI Key InChIKey=JGTRHUKCHHVVSS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50662111   

LigandChemical structure of BindingDB Monomer ID 50662111BDBM50662111(CHEMBL6133839)
Affinity DataIC50: 35nMAssay Description:Inhibition of human PRMT5/MEP50 using Histone H2A as substrate preincubated for 1 hr in presence of SAM/MTA followed by substrate addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50662111BDBM50662111(CHEMBL6133839)
Affinity DataIC50: 220nMAssay Description:Inhibition of human PRMT5/MEP50 using Histone H2A as substrate preincubated for 1 hr in presence of SAM followed by substrate addition and measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed