BDBM50662422 CHEMBL6167401

SMILES C=CC(=O)Nc1cccc(C(=O)Nc2cccc(-n3cc(NC(=O)Nc4cccc5ccccc45)cn3)c2)c1

InChI Key InChIKey=LTNDTFYBIKTRBQ-UHFFFAOYSA-N

Data  9 IC50  3 Kd  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50662422   

TargetMitogen-activated protein kinase 10(Human)
Eberhard Karls Universitat Tubingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662422BDBM50662422(CHEMBL6167401)
Affinity DataKd:  5.5nMAssay Description:Binding affinity to JNK3 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Eberhard Karls Universitat Tubingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662422BDBM50662422(CHEMBL6167401)
Affinity DataKd:  15nMAssay Description:Binding affinity to JNK2 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Eberhard Karls Universitat Tubingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662422BDBM50662422(CHEMBL6167401)
Affinity DataIC50: 25nMAssay Description:Time dependent inhibition of JNK2 (unknown origin) using sulfonamido-oxine fluorophore as substrate preincubated for 60 mins in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMitogen-activated protein kinase 10(Human)
Eberhard Karls Universitat Tubingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662422BDBM50662422(CHEMBL6167401)
Affinity DataIC50: 40nMAssay Description:Time dependent inhibition of JNK3 (unknown origin) using sulfonamido-oxine fluorophore as substrate preincubated for 60 mins in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
Eberhard Karls Universitat Tubingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662422BDBM50662422(CHEMBL6167401)
Affinity DataKd:  640nMAssay Description:Binding affinity to JNK1 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Eberhard Karls Universitat Tubingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662422BDBM50662422(CHEMBL6167401)
Affinity DataIC50: 830nMAssay Description:Inhibition of JNK2 (unknown origin) using ATF2 as substrate incubated for 60 mins by PamQuinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Eberhard Karls Universitat Tubingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662422BDBM50662422(CHEMBL6167401)
Affinity DataEC50:  883nMAssay Description:Inhibition of JNK2 (unknown origin) in presence of K10 tracer by NanoBRET TE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMitogen-activated protein kinase 10(Human)
Eberhard Karls Universitat Tubingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662422BDBM50662422(CHEMBL6167401)
Affinity DataIC50: 1.91E+3nMAssay Description:Inhibition of JNK3 (unknown origin) using ATF2 as substrate incubated for 60 mins by PamQuinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
Eberhard Karls Universitat Tubingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662422BDBM50662422(CHEMBL6167401)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of JNK1 (unknown origin) in presence of K10 tracer by NanoBRET TE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
Eberhard Karls Universitat Tubingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662422BDBM50662422(CHEMBL6167401)
Affinity DataIC50: 1.00E+4nMAssay Description:Time dependent inhibition of JNK1 (unknown origin) using sulfonamido-oxine fluorophore as substrate measured immediatelyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMitogen-activated protein kinase 10(Human)
Eberhard Karls Universitat Tubingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662422BDBM50662422(CHEMBL6167401)
Affinity DataIC50: 1.00E+4nMAssay Description:Time dependent inhibition of JNK3 (unknown origin) using sulfonamido-oxine fluorophore as substrate measured immediatelyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
Eberhard Karls Universitat Tubingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662422BDBM50662422(CHEMBL6167401)
Affinity DataIC50: 1.00E+4nMAssay Description:Time dependent inhibition of JNK1 (unknown origin) using sulfonamido-oxine fluorophore as substrate preincubated for 60 mins in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Eberhard Karls Universitat Tubingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662422BDBM50662422(CHEMBL6167401)
Affinity DataIC50: 1.00E+4nMAssay Description:Time dependent inhibition of JNK2 (unknown origin) using sulfonamido-oxine fluorophore as substrate measured immediatelyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
Eberhard Karls Universitat Tubingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662422BDBM50662422(CHEMBL6167401)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of JNK1 (unknown origin) using ATF2 as substrate incubated for 60 mins by PamQuinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed