BDBM50662459 CHEMBL6163694

SMILES Cn1cc(-c2cnc(N)c3c2OCCN([C@H]2CCC[C@@H]2OCc2ccc(-c4ccc(C(C)(C)N5CCN(CCO)CC5)cc4)cc2)C3)cn1

InChI Key InChIKey=JVDWGTWEAFXZTC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50662459   

TargetTyrosine-protein kinase Mer(Human)
Abbvie, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662459BDBM50662459(CHEMBL6163694)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of N-terminal GST-fused recombinant human MerTk cytoplasmic domain (528 to end residues) expressed in baculovirus expression system using ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Abbvie, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662459BDBM50662459(CHEMBL6163694)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of N-terminal His-tagged recombinant human Axl (473 to end residues) expressed in baculovirus-infected Sf9 cells using biotin-labeled TK a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed