BDBM50662476 CHEMBL6151959

SMILES Cn1cc(-c2cnc(N)c(C(=O)N[C@H]3CCC[C@@H]3OCc3ccc(-c4ccc([C@@H](N5CCN(CCO)CC5)C(F)(F)F)cc4)cc3)c2)cn1

InChI Key InChIKey=IYAFHTAESBHUML-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50662476   

TargetTyrosine-protein kinase Mer(Human)
Abbvie, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662476BDBM50662476(CHEMBL6151959)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of N-terminal GST-fused recombinant human MerTk cytoplasmic domain (528 to end residues) expressed in baculovirus expression system using ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Abbvie, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662476BDBM50662476(CHEMBL6151959)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of N-terminal His-tagged recombinant human Axl (473 to end residues) expressed in baculovirus-infected Sf9 cells using biotin-labeled TK a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed