BDBM50662926 CHEMBL6166134

SMILES Cc1ccc(-n2nccn2)c(C(=O)N2CCCN(c3nc4cc(Cl)ccc4o3)C[C@@H]2C)c1

InChI Key InChIKey=WSFZJZALHUICKW-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50662926   

TargetOrexin/Hypocretin receptor type 1(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662926BDBM50662926(CHEMBL6166134)
Affinity DataIC50: 0.830nMAssay Description:Displacement of [3H]SB-674042 from recombinant human OX1R extracted from HEK293T membrane by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662926BDBM50662926(CHEMBL6166134)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]5IBOM from OX1R (unknown origin) transfected in CHO cells assessed as inhibition constant incubated for 1.5 hrs by automated gamm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetOrexin receptor type 2(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662926BDBM50662926(CHEMBL6166134)
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]EMPA from recombinant human OX2R extracted from HEK293T membrane by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetOrexin receptor type 2(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662926BDBM50662926(CHEMBL6166134)
Affinity DataKi:  9.80nMAssay Description:Displacement of [3H]5IBOM from OX2R (unknown origin) transfected in CHO cells assessed as inhibition constant incubated for 1.5 hrs by automated gamm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed