BDBM50663239 CHEMBL6167626

SMILES COc1ccc(-c2ccc3cc(OCCCCCC(=O)NO)ccc3n2)cc1

InChI Key InChIKey=PNOJELYFZBJMEM-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50663239   

TargetHistone deacetylase 1(Human)
Central University of Punjab

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663239BDBM50663239(CHEMBL6167626)
Affinity DataIC50: 12nMAssay Description:Inhibition of HDAC1 extracted from human A549 nucleus incubated for 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Central University of Punjab

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663239BDBM50663239(CHEMBL6167626)
Affinity DataIC50: 23nMAssay Description:Inhibition of HDAC6 (unknown origin) using acetylated-peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
Central University of Punjab

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663239BDBM50663239(CHEMBL6167626)
Affinity DataIC50: 58nMAssay Description:Inhibition of recombinant human HDAC11 by fluorogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Central University of Punjab

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663239BDBM50663239(CHEMBL6167626)
Affinity DataIC50: 77nMAssay Description:Inhibition of His-tagged human HDAC2 by fluorogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Central University of Punjab

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663239BDBM50663239(CHEMBL6167626)
Affinity DataIC50: 87nMAssay Description:Inhibition of N-terminal FLAG-tagged recombinant human HDAC10 (2 to 631 residues) extracted from baculovirus infected Sf9 cells by fluorogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Central University of Punjab

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663239BDBM50663239(CHEMBL6167626)
Affinity DataIC50: 88nMAssay Description:Inhibition of His/GST-tagged recombinant human HDAC3/NcoR2 by fluorogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
Central University of Punjab

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663239BDBM50663239(CHEMBL6167626)
Affinity DataIC50: 88nMAssay Description:Inhibition of His-tagged recombinant human HDAC5 catalytic domain by fluorogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Central University of Punjab

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663239BDBM50663239(CHEMBL6167626)
Affinity DataIC50: 99nMAssay Description:Inhibition of His/GST-tagged recombinant human HDAC4 by fluorogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 9(Human)
Central University of Punjab

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663239BDBM50663239(CHEMBL6167626)
Affinity DataIC50: 100nMAssay Description:Inhibition of His-tagged recombinant human HDAC9 by fluorogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Central University of Punjab

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663239BDBM50663239(CHEMBL6167626)
Affinity DataIC50: 500nMAssay Description:Inhibition of HDAC8 (unknown origin) by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Central University of Punjab

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663239BDBM50663239(CHEMBL6167626)
Affinity DataIC50: 6.78E+4nMAssay Description:Inhibition of human Topo II-alpha-mediated decatenation of kDNA incubated for 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed