BDBM506636 Methyl 3-(((R)-1- ((1R,3S,5S,6r)-3-(5,6- difluoro-1H-benzo[d]- imidazol-1-yl)bicyclo- [3.1.0]hexan-6-yl)propyl)- carbamoyl)bicyclo[1.1.1]- pentane-1-carboxylate::US11046649, Ex. 14

SMILES CN1CCN(CCCCc2cn(-c3ccccc3)c(NC(=O)c3cccc(-c4cnn(C)c4)c3)n2)CC1

InChI Key InChIKey=LIOVQCCGJNPPPL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 506636   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 506636BDBM506636(US12534452, Example 221)
Affinity DataIC50: 50nMAssay Description:The mGluR5 activity was determined using the metabotropic glutamate receptor activity assays in human embryonic kidney cell.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2026
Entry Details US Patent