BDBM50663903 CHEMBL6170056

SMILES C[C@H]1C(=O)N(c2cnc(nc2N1CCC(C)C)Nc3cc(c(c(c3)F)O)F)C

InChI Key InChIKey=DTEKTGDVSARYDS-UHFFFAOYSA-N

Data  2 IC50

PDB links: 3 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50663903   

TargetSerine/threonine-protein kinase VRK1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663903BDBM50663903(CHEMBL6170056)
Affinity DataIC50: 112nMAssay Description:Inhibition of VRK1 (3 to 364 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3)-R3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase VRK2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663903BDBM50663903(CHEMBL6170056)
Affinity DataIC50: 196nMAssay Description:Inhibition of VRK2 (14 to 335 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3)-R3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)