BDBM506645 N-(3-cyanobicyclo- [1.1.1]pentan-1-yl)-2- ((1R,3s,5S,6r)-3-(5,6- difluoro-1H-benzo[d]- imidazol-1-yl)bicyclo- [3.1.0]hexan-6-yl)- propanamide::US11046649, Ex. 23

SMILES O=C(CCCc1cn(-c2ccccc2)c(NC(=O)c2cccc(-c3cn[nH]c3F)c2)n1)NC1CC1

InChI Key InChIKey=NNXHWOHMQUVGOE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 506645   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 506645BDBM506645(US12534452, Example 229)
Affinity DataIC50: 50nMAssay Description:The mGluR5 activity was determined using the metabotropic glutamate receptor activity assays in human embryonic kidney cell.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2026
Entry Details US Patent