BDBM50664859 CHEMBL6163208

SMILES COc1ncc(-c2ccc3ncnc(N[C@H]4CCN(C(=O)C5CCOCC5)C4)c3n2)cc1C(=O)Oc1cccnc1

InChI Key InChIKey=ZBEDIAIAAVITRB-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50664859   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Xi'an Jiaotong University

Curated by ChEMBL

LigandBDBM50664859(CHEMBL6163208)Copy SMILESCopy InChI

Affinity DataIC50: 0.700nMAssay Description:Inhibition of recombinant PI3Kdelta (unknown origin) using PIP2:3PS as substrate preincubated for 20 mins followed by ATP addition and measured after...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
6/6/2026
Entry Details
Copy BDB DOIPubMed
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Xi'an Jiaotong University

Curated by ChEMBL

LigandBDBM50664859(CHEMBL6163208)Copy SMILESCopy InChI

Affinity DataIC50: 254nMAssay Description:Inhibition of recombinant PI3Kalpha (unknown origin) using PIP2:3PS as substrate preincubated for 20 mins followed by ATP addition and measured after...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
6/6/2026
Entry Details
Copy BDB DOIPubMed
Copy reaction URL