BDBM50664927 CHEMBL6159522

SMILES O=C(CN1C(=O)/C(=NNC(=O)c2cc(Br)ccc2O)c2c(Br)cccc21)Nc1ccc([N+](=O)[O-])cc1

InChI Key InChIKey=QFZVGQPUWIBQFU-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50664927   

TargetSmoothened homolog(Human)
University of Campania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664927BDBM50664927(CHEMBL6159522)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]-cyclopamine from SMO receptor (unknown origin) expressed in HEK293T cell membranes measured after 4 hrs by liquid scintillation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
University of Campania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664927BDBM50664927(CHEMBL6159522)
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of human N-terminal GST-fused MET cytoplasmic domain (956 to 1390 residues) expressed in baculovirus expression system measured after 1 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed