BDBM50665133 CHEMBL6151225

SMILES CC(C)(O)c1ccc(S(=O)(=O)NC(=O)Nc2c3c(cc4c2CCC4)CCC3)o1

InChI Key InChIKey=ROWBZVZYNJNHTM-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50665133   

TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Guangzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665133BDBM50665133(CHEMBL6151225)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of NLRP3 in mouse J774.A1 cells assessed as reduction IL-1beta release by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Guangzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665133BDBM50665133(CHEMBL6151225)
Affinity DataKd:  23nMAssay Description:Binding affinity to CM5 chip-immobilized NLRP3 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed