BDBM50665163 CHEMBL6169322

SMILES CC[C@H](NC(=O)c1c(C)c(-c2cccc(F)c2)nc2c([N+](=O)[O-])cccc12)c1ccccc1

InChI Key InChIKey=HWLIEWJEGCLWFD-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50665163   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Guangzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665163BDBM50665163(CHEMBL6169322)
Affinity DataKd:  28nMAssay Description:Binding affinity to CM5 chip-immobilized NLRP3 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Guangzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665163BDBM50665163(CHEMBL6169322)
Affinity DataIC50: 180nMAssay Description:Inhibition of NLRP3 in mouse J774.A1 cells assessed as reduction IL-1beta release by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed