BDBM50665249 CHEMBL6174342

SMILES O=C(NO)c1cccc2[nH]c(C#Cc3cccc(C(F)(F)F)c3)cc12

InChI Key InChIKey=XLRSFMDEDSFKAM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50665249   

TargetHistone deacetylase 11(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665249BDBM50665249(CHEMBL6174342)
Affinity DataIC50: 4nMAssay Description:Inhibition of full length human recombinant HDAC11 (1 to 347 end residues) expressed in Sf9 cells using AcetylETDKmyr-AMC as substrate preincubated w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665249BDBM50665249(CHEMBL6174342)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of N-terminal GST-tagged full length human recombinant HDAC6 (1 to 1215 end residues) expressed in Sf9 cells using Boc-Lys-(acetyl)-AMC as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665249BDBM50665249(CHEMBL6174342)
Affinity DataIC50: 2.24E+4nMAssay Description:Inhibition of C-terminal His-tagged full length human recombinant HDAC8 (1 to 377 end residues) expressed in Sf9 cells using Boc-Lys-(trifluoroacetyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665249BDBM50665249(CHEMBL6174342)
Affinity DataIC50: 3.73E+4nMAssay Description:Inhibition of C-terminal 6xHis/FLAG-tagged full length human recombinant HDAC1 (1 to 482 end residues) expressed in Sf9 cells using Boc-Lys-(acetyl)-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665249BDBM50665249(CHEMBL6174342)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal GST-tagged C-terminal His-tagged human HDAC4 (627 to 1084 end residues) expressed in baculovirus expression system in Sf9 ce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed