BDBM50665504 CHEMBL6168377

SMILES C=CCn1c(=O)c2cnc(Nc3ccc4c(c3)CN(C)CC43CC3)nc2n1-c1cccc(C2(O)COC2)n1

InChI Key InChIKey=AHASZNFGKFRVOQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50665504   

TargetWee1-like protein kinase(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665504BDBM50665504(CHEMBL6168377)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human WEE1 kinase extracted from in presence of [gamma33P]ATP by radiometric protein kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665504BDBM50665504(CHEMBL6168377)
Affinity DataIC50: 760nMAssay Description:Inhibition of recombinant human PLK1 kinase extracted from in presence of [gamma33P]ATP by radiometric protein kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665504BDBM50665504(CHEMBL6168377)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human CHK1 kinase extracted from in presence of [gamma33P]ATP by radiometric protein kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed