BDBM50665539 CHEMBL6146605

SMILES O[C@H]1CC[C@H](Nc2nc(Nc3cccc(Cl)c3)ncc2C2CCN(CC3CCCC3)CC2)CC1

InChI Key InChIKey=SCQHXMIMWDQIRJ-UHFFFAOYSA-N

Data  4 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50665539   

TargetTyrosine-protein kinase receptor TYRO3(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665539BDBM50665539(CHEMBL6146605)
Affinity DataEC50: <0.510nMAssay Description:Displacement of tracer K-5 from TYRO3 (unknown origin) transfected in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein kinase Mer(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665539BDBM50665539(CHEMBL6146605)
Affinity DataEC50: <0.510nMAssay Description:Displacement of tracer K-5 from MERTK (unknown origin) transfected in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein kinase Mer(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665539BDBM50665539(CHEMBL6146605)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of MERTK (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate incubated for 180 mins in presence of ATP by MCE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein kinase receptor TYRO3(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665539BDBM50665539(CHEMBL6146605)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of TYRO3 (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate incubated for 180 mins in presence of ATP by MCE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665539BDBM50665539(CHEMBL6146605)
Affinity DataIC50: 51nMAssay Description:Inhibition of AXL (unknown origin) using 5-FAM-KKKKEEIYFFF-CONH2 as substrate incubated for 180 mins in presence of ATP by MCE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665539BDBM50665539(CHEMBL6146605)
Affinity DataIC50: 440nMAssay Description:Inhibition of FLT3 (unknown origin) using 5-FAM-KKKKEEIYFFF-CONH2 as substrate incubated for 180 mins in presence of ATP by MCE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665539BDBM50665539(CHEMBL6146605)
Affinity DataEC50:  1.51E+3nMAssay Description:Displacement of tracer K-5 from AXL (unknown origin) transfected in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed