BDBM50665600 CHEMBL6175778

SMILES Cc1ccc(C(C)C)cc1Oc1nccc(-c2c(-c3ccc(C(F)(F)F)cc3)ncn2C2CCN(CCO)CC2)n1

InChI Key InChIKey=ZGDFKJDTBBCIQY-UHFFFAOYSA-N

Data  1 KI  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50665600   

TargetBromodomain-containing protein 4(Human)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665600BDBM50665600(CHEMBL6175778)
Affinity DataIC50: 111nMAssay Description:Inhibition of his9-tagged BRD4-BD1 (unknown origin) preincubated for 30 mins followed by addition of biotinylated peptide and measured after 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665600BDBM50665600(CHEMBL6175778)
Affinity DataKi:  936nMAssay Description:Binding affinity to N-luc fused BRD4-BD1 in HEK293T cells assessed as apparent inhibition constant using NanoGlo substrate as substrate incubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665600BDBM50665600(CHEMBL6175778)
Affinity DataEC50:  2.45E+3nMAssay Description:Inhibition of N-luc fused BRD4-BD1 in HEK293T cells using NanoGlo substrate as substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665600BDBM50665600(CHEMBL6175778)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human his tagged BRD4-BD2 using Histone H4 peptide (1-21) K5/8/12/16Ac as substrate preincubated for 30 mins followed by addition of bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBromodomain-containing protein 2(Human)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665600BDBM50665600(CHEMBL6175778)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of his9-tagged BRD2-BD2 (unknown origin) preincubated for 30 mins followed by addition of biotinylated peptide and measured after 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed