BDBM50665623 CHEMBL6176840

SMILES Cn1cncc1-c1cc(-c2ccc(F)cc2F)cc2c1CNC2=O

InChI Key InChIKey=UYPRIXVJTXCLQJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50665623   

TargetMetabotropic glutamate receptor 2(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665623BDBM50665623(CHEMBL6176840)
Affinity DataIC50: 34nMAssay Description:Negative allosteric modulation of human mGlu2R expressed in HEK293 cells co-expressing GIRK assessed as reduction in glutamate-induced thallium flux ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665623BDBM50665623(CHEMBL6176840)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of human mGlu3R expressed in HEK293 cells co-expressing GIRK assessed as reduction in glutamate-induced thallium flux ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed