BDBM50665893 CHEMBL6171564

SMILES COc1cc2c(=O)c3cc(C)cc(C(=O)O)c3[nH]c2c(C)c1C

InChI Key InChIKey=LCPSBGGOOZLNLK-UHFFFAOYSA-N

Data  1 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50665893   

TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665893BDBM50665893(CHEMBL6171564)
Affinity DataEC50:  980nMAssay Description:Potentiation of cGAMP-induced human STING pathway activation expressed in HEK293 cells assessed as cGAMP EC50 at 100 uM incubated for 48 hrs by QUANT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetStimulator of interferon genes protein(Mouse)
Beijing Institute of Pharmacology & Toxicology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665893BDBM50665893(CHEMBL6171564)
Affinity DataEC50:  1.76E+3nMAssay Description:Potentiation of cGAMP-induced mouse STING pathway activation expressed in HEK293 cells assessed as cGAMP EC50 at 100 uM incubated for 48 hrs by QUANT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665893BDBM50665893(CHEMBL6171564)
Affinity DataEC50:  3.66E+3nMAssay Description:Potentiation of cGAMP-induced human STING pathway activation expressed in HEK293 cells assessed as cGAMP EC50 at 33 uM incubated for 48 hrs by QUANTI...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetStimulator of interferon genes protein(Mouse)
Beijing Institute of Pharmacology & Toxicology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665893BDBM50665893(CHEMBL6171564)
Affinity DataEC50:  4.02E+3nMAssay Description:Potentiation of cGAMP-induced mouse STING pathway activation expressed in HEK293 cells assessed as cGAMP EC50 at 33 uM incubated for 48 hrs by QUANTI...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Beijing Institute of Pharmacology & Toxicology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665893BDBM50665893(CHEMBL6171564)
Affinity DataIC50: 5.95E+3nMAssay Description:Binding affinity to His-tagged STING (unknown origin) incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed