BDBM50665981 CHEMBL6145572

SMILES COCC(N)c1cncc(NC(=O)c2c(N)ncn(-c3c(Cl)cc(OC4CC4)cc3Cl)c2=O)c1

InChI Key InChIKey=RURJMUCIKWMHPY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50665981   

TargetGlycogen synthase kinase-3 alpha(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665981BDBM50665981(CHEMBL6145572)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of full length human GSK3alpha extracted from baculovirus expression system using 5-FAM-KRREILSRRPpSYR-COOH as substrate preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665981BDBM50665981(CHEMBL6145572)
Affinity DataIC50: 166nMAssay Description:Inhibition of Nanoluc-GSK2beta (unknown origin) expressed in HEK293 cells measured after overnight incubation by NanoBRET- cellular assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665981BDBM50665981(CHEMBL6145572)
Affinity DataIC50: 203nMAssay Description:Inhibition of full length human GSK3beta extracted from baculovirus expression system using 5-FAM-KRREILSRRPpSYR-COOH as substrate preincubated for 4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed