BDBM50665994 CHEMBL6175193

SMILES C[C@H](c1cccnc1N)N(C)c1nc(OC[C@@]23CCCN2C[C@H](F)C3)nc(N2CC(C)(c3csc(N)c3C#N)C2)c1C#N

InChI Key InChIKey=SRXNCXPRFAPSBE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50665994   

TargetKRas/Son of Sevenless Homolog 1(Human)
Usona Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665994BDBM50665994(CHEMBL6175193)
Affinity DataIC50: 10nMAssay Description:Inhibition of GST-tagged KRAS G12D mutant (2 to 169 residues) (unknown origin)/SOS1 catalytic domain (564 to 1069 residues) (unknown origin) protein-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed