BDBM50666016 CHEMBL6177624

SMILES c1cc2c(cc1-c1cnc3[nH]nc(-c4ccc(N5CC6(COC6)C5)cc4)c3c1)CC[C@@H](N1C3COCC1C3)CC2

InChI Key InChIKey=JWGYPLFCSLKHGA-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50666016   

TargetTyrosine-protein kinase receptor UFO(Human)
Arcus Biosciences, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666016BDBM50666016(CHEMBL6177624)
Affinity DataIC50: 27nMAssay Description:Inhibition of human AXL measured after 150 mins by ATP-competitive HTRF based biochemical assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Arcus Biosciences, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666016BDBM50666016(CHEMBL6177624)
Affinity DataKd:  120nMAssay Description:Binding affinity to AXL (unknown origin) expressed in HEK293 cells transfected with Nano-Luc fusion vector assessed as dissociation constant by measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed