BDBM50666039 CHEMBL6176798
SMILES COc1ncc(-c2ccc3ncnc(N[C@H]4CCN(C(=O)C5CCN(CCCCCCCCCC(=O)N[C@H](C(=O)N6C[C@H](O)C[C@H]6C(=O)N[C@@H](C)c6ccc(-c7scnc7C)cc6)C(C)(C)C)CC5)C4)c3n2)cc1C(=O)Oc1ccccc1
InChI Key InChIKey=KNDPLYQCLBUGGT-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50666039
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Xi'an Jiaotong University
Curated by ChEMBL
Xi'an Jiaotong University
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of PI3Kdelta (unknown origin) preincubated for 30 mins followed by ATP addition and measured after 1 hrs by ADP-Glo reagent based analysisMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Xi'an Jiaotong University
Curated by ChEMBL
Xi'an Jiaotong University
Curated by ChEMBL
Affinity DataIC50: 589nMAssay Description:Inhibition of PI3Kalpha (unknown origin) preincubated for 30 mins followed by ATP addition and measured after 1 hrs by ADP-Glo reagent based analysisMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Xi'an Jiaotong University
Curated by ChEMBL
Xi'an Jiaotong University
Curated by ChEMBL
Affinity DataIC50: 605nMAssay Description:Inhibition of PI3Kgamma (unknown origin) preincubated for 30 mins followed by ATP addition and measured after 1 hrs by ADP-Glo reagent based analysisMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Xi'an Jiaotong University
Curated by ChEMBL
Xi'an Jiaotong University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3Kbeta (unknown origin) preincubated for 30 mins followed by ATP addition and measured after 1 hrs by ADP-Glo reagent based analysisMore data for this Ligand-Target Pair