BDBM50666741 CHEMBL6177352

SMILES COc1ccc(-c2nnc(N[C@@H]3CCCN(C)C3)c3nccn23)c(O)c1

InChI Key InChIKey=LBURYRMIAYTCRA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50666741   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
A Johnson & Johnson Company

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666741BDBM50666741(CHEMBL6177352)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of NLRP3 in LPS-induced human PBMC cells assessed as inhibition of IL-1beta secretion pretreated with compound for 30 mins followed by LPS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed