BDBM50666811 CHEMBL6162062

SMILES CCNNC(=O)c1ccc(cc1)CN(CC(=O)NCc2ccccc2)C(=O)c3ccc(cc3)N(C)C

InChI Key InChIKey=CEUILOOLSJTSTF-UHFFFAOYSA-N

Data  11 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50666811   

TargetHistone deacetylase 3(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666811BDBM50666811(CHEMBL6162062)
Affinity DataIC50: 23nMAssay Description:Inhibition of human HDAC3 using ZMAL(Z-Lys(Ac)-AMC as substrate preincubated for 60 mins followed by substrate addition and measured after 90 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666811BDBM50666811(CHEMBL6162062)
Affinity DataIC50: 29nMAssay Description:Inhibition of human HDAC1 using ZMAL(Z-Lys(Ac)-AMC as substrate preincubated for 60 mins followed by substrate addition and measured after 90 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666811BDBM50666811(CHEMBL6162062)
Affinity DataIC50: 160nMAssay Description:Inhibition of HDAC in human Cal27CisR cells using Boc-Lys(Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666811BDBM50666811(CHEMBL6162062)
Affinity DataIC50: 220nMAssay Description:Inhibition of HDAC in human CAL-27 cells using Boc-Lys(Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition and measured after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666811BDBM50666811(CHEMBL6162062)
Affinity DataIC50: 277nMAssay Description:Inhibition of HDAC in human A2780 cisR cells using Boc-Lys(Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition and measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666811BDBM50666811(CHEMBL6162062)
Affinity DataIC50: 367nMAssay Description:Inhibition of human HDAC6 using ZMAL(Z-Lys(Ac)-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 90 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666811BDBM50666811(CHEMBL6162062)
Affinity DataIC50: 402nMAssay Description:Inhibition of HDAC in human A2780 cells using Boc-Lys(Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666811BDBM50666811(CHEMBL6162062)
Affinity DataIC50: 575nMAssay Description:Inhibition of HDAC in human CAL-27 cells using Boc-Lys(TFA)-AMC as substrate preincubated for 18 hrs followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666811BDBM50666811(CHEMBL6162062)
Affinity DataIC50: 607nMAssay Description:Inhibition of HDAC in human Cal27CisR cells using Boc-Lys(TFA)-AMC as substrate preincubated for 18 hrs followed by substrate addition and measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666811BDBM50666811(CHEMBL6162062)
Affinity DataIC50: 2.91E+3nMAssay Description:Inhibition of HDAC in human A2780 cisR cells using Boc-Lys(TFA)-AMC as substrate preincubated for 18 hrs followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666811BDBM50666811(CHEMBL6162062)
Affinity DataIC50: 2.97E+3nMAssay Description:Inhibition of HDAC in human A2780 cells using Boc-Lys(TFA)-AMC as substrate preincubated for 18 hrs followed by substrate addition and measured after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed