BDBM50666918 CHEMBL6174282

SMILES COc1cc(C(=O)N2CCC(N3CCCC3)CC2)ccc1OCc1c(C)noc1C

InChI Key InChIKey=QKRFITNUAUMQEG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50666918   

TargetToll-like receptor 8(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666918BDBM50666918(CHEMBL6174282)
Affinity DataIC50: 3.46E+3nMAssay Description:Antagonist activity at TLR8 in HEK-Blue hTLR8 cells assessed as inhibition of TL8-506 induced NF-kappaB activation preincubated with compound for 1 h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed