BDBM50666967 CHEMBL6161660

SMILES Cc1ccc(CNC(=O)c2cnc(OCS(=O)(=O)c3ccc(F)c(Cl)c3)c(C)n2)cn1

InChI Key InChIKey=DMVGETQJHCVGGG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50666967   

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Janssen Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666967BDBM50666967(CHEMBL6161660)
Affinity DataIC50: 20nMAssay Description:Negative allosteric modulation of human GluN1/GluN2A expressed in T-REx-CHO-K1 cells by fluorometric calcium mobilization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666967BDBM50666967(CHEMBL6161660)
Affinity DataIC50: 2.80E+4nMAssay Description:Negative allosteric modulation of human GluN1/GluN2B expressed in T-REx-CHO-K1 cells by fluorometric calcium mobilization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed