BDBM50667126 CHEMBL6169637

SMILES Cn1c(-c2ccc3c(c2O)CCC3)nnc(N[C@@H]2CCCN(CCO)C2)c1=O

InChI Key InChIKey=QPWRSZGTQUEOPL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50667126   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667126BDBM50667126(CHEMBL6169637)
Affinity DataIC50: 11nMAssay Description:Inhibition of NLRP3 in human THP-1 cells assessed as inhibition of nigericin-induced pyroptosis measured after 24 hrs by resazurin staining based ana...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed