BDBM50667129 CHEMBL6172133

SMILES CC(=O)N1CCC[C@@H](Nc2nnc(-c3ccc4c(c3O)CCC4)n(C)c2=O)C1

InChI Key InChIKey=VCKOHGDTVQFVEU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50667129   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667129BDBM50667129(CHEMBL6172133)
Affinity DataIC50: 51nMAssay Description:Inhibition of NLRP3 in human THP-1 cells assessed as inhibition of nigericin-induced pyroptosis measured after 24 hrs by resazurin staining based ana...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed