BDBM50667708 CHEMBL6191997

SMILES CN(C)[C@@H]1CCN(c2ccc(-n3cnc(Nc4cnc(C#N)cn4)c3)nc2)C1

InChI Key InChIKey=INAQSAXLYAIEJV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50667708   

TargetSerine/threonine-protein kinase Chk1(Human)
BenevolentAI

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667708BDBM50667708(CHEMBL6191997)
Affinity DataIC50: 4nMAssay Description:Inhibition of N-terminal GST-fused human full length CHK1 (1 to 476 residues) expressed in baculovirus-infected Sf21 cells using STK1 S1 as substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
BenevolentAI

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667708BDBM50667708(CHEMBL6191997)
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of N-terminal GST-fused human full length CHK2 (1 to 543 residues) expressed in baculovirus-infected Sf21 cells using STK1 S1 as substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed