BDBM50667936 CHEMBL6188703

SMILES CNC(=O)C(C)n1cc(Nc2nc(N[C@H]3CCc4ccccc43)c3cc[nH]c3n2)cn1

InChI Key InChIKey=OMLUQIFWMNNNQG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50667936   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Duke University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667936BDBM50667936(CHEMBL6188703)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant wild type GST-LRRK2 (unknown origin) purified from baculovirus infected Sf9 cells assessed as autophosphorylation using RLG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Duke University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667936BDBM50667936(CHEMBL6188703)
Affinity DataIC50: 13nMAssay Description:Inhibition of LRRK2 G2019S mutant (unknown origin) purified from baculovirus infected Sf9 cells assessed as autophosphorylation using RLGAWRFYTLRRARQ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed