BDBM50667976 CHEMBL6193303

SMILES O=C(Cn1c2c(c(=O)n3nc(C4=CCOCC4)nc13)C1(CCN(C(=O)Cc3ccc(Cl)nn3)CC1)OCC2)Nc1ccc(C2CC2)cc1Cl

InChI Key InChIKey=ITHOOXYLDBKKBE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50667976   

TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Smith, Gambrell & Russell LLP

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667976BDBM50667976(CHEMBL6193303)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of WRN helicase (500 to 942 residues)(unknown origin) using fluor/quencher-labeled forked double-stranded DNA substrate assessed as decrea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed