BDBM50667983 CHEMBL6191419

SMILES Cc1nc([C@@H]2CCON2C(=O)C2CCN(c3ncnc(-n4ccnc4)n3)CC2)cs1

InChI Key InChIKey=MDLFXRKDNOBDNF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50667983   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667983BDBM50667983(CHEMBL6191419)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of recombinant human RIPK1 (1 to 375 residues) preincubated for 30 mins followed by ATP addition measured after 240 mins by ADP Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed