BDBM50668155 CHEMBL6193251

SMILES COc1cc2sc(C(=O)NCCC(=O)O)c(F)c2cc1OC

InChI Key InChIKey=KJLZKQLYGGJWHO-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50668155   

TargetStimulator of interferon genes protein(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668155BDBM50668155(CHEMBL6193251)
Affinity DataEC50:  3.03E+4nMAssay Description:Agonist activity at human STING in human THP1-Blue ISG cells measured after 24 hrs incubation by QUANTI-Blue based microplate readerMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668155BDBM50668155(CHEMBL6193251)
Affinity DataEC50:  3.03E+4nMAssay Description:Agonist activity at human STING HAQ variant in human THP1-Blue ISG cells assessed as fold change in stimulation activity measured after 24 hrs incuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668155BDBM50668155(CHEMBL6193251)
Affinity DataIC50: 4.98E+4nMAssay Description:Binding affinity to wild type His-tagged STING (unknown origin) measured after 3 hrs incubation by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed