BDBM50668662 CHEMBL6189801

SMILES Oc1c(-c2nnc(N[C@H]3CCCC[C@@H]3O)c3cnccc23)ccc2c1CC2

InChI Key InChIKey=BXIJUAQGKWFISC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50668662   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668662BDBM50668662(CHEMBL6189801)
Affinity DataIC50: 3nMAssay Description:Inhibition of NLRP3 in human whole blood assessed as decrease in IL-1beta level incubated for 3 hrs followed by nigericin stimulation for 1 hr by Alp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed