BDBM50668728 CHEMBL6190233

SMILES CC(C)(C)c1ccc(N2C(=O)c3ccccc3C(C(N)=O)C2c2cc3cc(-c4ccc(C(=O)Nc5ccc(O)c(NS(C)(=O)=O)c5)cc4)ccc3o2)cc1Cl

InChI Key InChIKey=KHDQXFGPHMQVDM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50668728   

TargetStimulator of interferon genes protein(Mouse)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668728BDBM50668728(CHEMBL6190233)
Affinity DataIC50: 20nMAssay Description:Inhibition of cGAMP-induced mouse STING transfected in human THP-1 cells preincubated with compound for 6 hrs followed by cGAMP addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668728BDBM50668728(CHEMBL6190233)
Affinity DataIC50: 30nMAssay Description:Inhibition of cGAMP-induced STING R232 mutant transfected human THP-1 cells preincubated with compound for 6 hrs followed by cGAMP addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668728BDBM50668728(CHEMBL6190233)
Affinity DataIC50: 100nMAssay Description:Inhibition of cGAMP-induced STING HAQ mutant transfected in human THP1-Blue ISG cells preincubated with compound for 6 hrs followed by cGAMP addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668728BDBM50668728(CHEMBL6190233)
Affinity DataIC50: 110nMAssay Description:Inhibition of diABZI-induced STING HAQ mutant transfected in human THP1-Blue ISG cells preincubated with compound for 6 hrs followed by diABZI additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668728BDBM50668728(CHEMBL6190233)
Affinity DataIC50: 210nMAssay Description:Inhibition of cGAMP-induced STING S154 mutant transfected in human THP-1 cells preincubated with compound for 6 hrs followed by cGAMP addition and me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed