BDBM50668772 CHEMBL6190053

SMILES Cc1nc(-c2cc(F)c(F)c(O)c2F)sc1C(=O)N(Cc1ccccc1)C(C)C

InChI Key InChIKey=AGRNXDATIDGSHV-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50668772   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668772BDBM50668772(CHEMBL6190053)
Affinity DataIC50: 9.90nMAssay Description:Inhibition of human HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668772BDBM50668772(CHEMBL6190053)
Affinity DataKd:  68nMAssay Description:Binding affinity to human recombinant HSD17B13 assessed as dissociation constant measured after 10 to 15 mins by MST analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
Target17-beta-hydroxysteroid dehydrogenase 13(Mus musculus)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668772BDBM50668772(CHEMBL6190053)
Affinity DataIC50: 184nMAssay Description:Inhibition of mouse HSD17B13 using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed