BDBM50668796 CHEMBL6192256

SMILES O=C(c1ccc(/C=C/c2n[nH]c3ccc(-c4ccncc4)cc23)cc1)N1CCNCC1

InChI Key InChIKey=PUFICYMFIYMRQH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50668796   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668796BDBM50668796(CHEMBL6192256)
Affinity DataIC50: 0.780nMAssay Description:Inhibition of His-tagged human recombinant FLT3 catalytic domain (564 to 958 residues) expressed in insect cells using ATP as substrate incubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668796BDBM50668796(CHEMBL6192256)
Affinity DataIC50: 18nMAssay Description:Inhibition of FLT3 D835Y mutant (unknown origin) incubated for 120 mins by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed