BDBM50668819 CHEMBL6189235

SMILES Nc1cc(-c2ccc3c(/C=C/c4ccc(C(=O)N5CCOCC5)cc4)n[nH]c3c2)ccn1

InChI Key InChIKey=VLFNNWBYIXEZRM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50668819   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668819BDBM50668819(CHEMBL6189235)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of His-tagged human recombinant FLT3 catalytic domain (564 to 958 residues) expressed in insect cells using ATP as substrate incubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668819BDBM50668819(CHEMBL6189235)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of FLT3 D835Y mutant (unknown origin) incubated for 120 mins by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed