BDBM506689 (S)-2-((1R,3R,5S,6r)-3- (5,6-difluoro-1H-benzo[d]- imidazol-1-yl)- bicyclo[3.1.0]hexan-6-yl)- N-(4-(6-methylpyridin-3- yl)phenyl)propanamide::US11046649, Ex. 67

SMILES CN1CCN(C(=O)CCCCCc2cn(-c3ccccc3)c(NC(=O)c3cccc(-c4ccc(N)nc4)c3)n2)CC1

InChI Key InChIKey=WJYIBRPQAUXCED-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 506689   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 506689BDBM506689(US12534452, Example 272)
Affinity DataIC50: 50nMAssay Description:The mGluR5 activity was determined using the metabotropic glutamate receptor activity assays in human embryonic kidney cell.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2026
Entry Details US Patent