BDBM50668919 CHEMBL6190373

SMILES COc1cc2nccc(Oc3ccc(NC(=O)c4ccccc4OC)cc3F)c2cc1OC

InChI Key InChIKey=YKIGTROWEMZOLE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50668919   

TargetHepatocyte growth factor receptor(Human)
Kinnate Biopharma Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668919BDBM50668919(CHEMBL6190373)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human c-MET D1228N mutant (956 to end residues) extracted from baculovirus infected Sf9 cells using 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Kinnate Biopharma Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668919BDBM50668919(CHEMBL6190373)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of N-terminal GST-tagged wild-type human c-MET (956 to 1390 residues) extracted from baculovirus infected Sf21 cells using 5-FAM-KKKKEEIYF...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein kinase Mer(Human)
Kinnate Biopharma Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668919BDBM50668919(CHEMBL6190373)
Affinity DataIC50: 250nMAssay Description:Inhibition of MERTK (unknown origin) by fluorescence-based microfluidic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Kinnate Biopharma Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668919BDBM50668919(CHEMBL6190373)
Affinity DataIC50: 250nMAssay Description:Inhibition of AXL (unknown origin) by fluorescence-based microfluidic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Kinnate Biopharma Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668919BDBM50668919(CHEMBL6190373)
Affinity DataIC50: 250nMAssay Description:Inhibition of KDR (unknown origin) by fluorescence-based microfluidic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed