BDBM50669010 CHEMBL6192325
SMILES Cc1c(N2CCCC2=O)cccc1S(=O)(=O)N[C@@H](CNC(=O)c1ccc(Cl)s1)C(=O)OCCS(C)(=O)=O
InChI Key InChIKey=CJXHOHJDCJCNHI-UHFFFAOYSA-N
Data 14 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50669010
Affinity DataIC50: 0.490nMAssay Description:Inhibition of human factor Xa in Tris buffer using Boc-Ile-Glu-GlyArg-AMC as substrate preincubated for 30 mins followed by substrate addition measur...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human factor Xa using Methoxycarbonyl-D-Nle-Gly-Arg-pNA as substrate measured for 20 mins in presence of human plasma by RVV reagent ba...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human factor IIa in Tris buffer using Boc-Asp(OBzl)-Pro-Arg-AMC as substrate preincubated for 15 mins followed by substrate addition me...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of human factor IIa using Boc-Val-Pro-Arg-AMC as substrate measured for 20 mins in presence of human plasma by ecarin reagent based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human factor IIa using Boc-Val-Pro-Arg-AMC as substrate measured for 20 mins in presence of rabbit plasma by ecarin reagent based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of human factor IIa using Boc-Val-Pro-Arg-AMC as substrate measured for 20 mins in presence of minipig plasma by ecarin reagent based assa...More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human factor Xa using Methoxycarbonyl-D-Nle-Gly-Arg-pNA as substrate measured for 20 mins in presence of minipig plasma by RVV reagent ...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of human factor Xa using Methoxycarbonyl-D-Nle-Gly-Arg-pNA as substrate measured for 20 mins in presence of rabbit plasma by RVV reagent b...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of factor IIa generation in human plasma using Z-Gly-Gly-Arg-AMC as substrate preincubated for 5 mins followed by calcium chloride additio...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of TPA (unknown origin) using CH3SO2-D-Phe-Gly-Arg-AMC as substrate preincubated for 15 mins followed by substrate addition measured after...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of trypsin (unknown origin) using Boc-Ile-Glu-Gly-Arg-AMC as substrate preincubated for 15 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of kallikrein (unknown origin) using H-Pro-Phe-Arg-AMC as substrate preincubated for 15 mins followed by substrate addition measured after...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of factor XIa (unknown origin) using Boc-Glu(OBzl)-Ala-Arg-AMC as substrate preincubated for 15 mins followed by substrate addition measur...More data for this Ligand-Target Pair
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of plasmin (unknown origin) using MeOSuc-Ala-Phe-Lys-AMC as substrate preincubated for 15 mins followed by substrate addition measured aft...More data for this Ligand-Target Pair