BDBM50669031 CHEMBL6191447

SMILES CN(C)C[C@@H]1CCN(c2cccc(S(=O)(=O)N[C@@H](CNC(=O)c3ccc(Cl)s3)C(=O)OCC[S@+](C)[O-])c2)C1=O

InChI Key InChIKey=WXBSNOMSWZXHSL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50669031   

TargetProthrombin(Human)
Germany.F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50669031BDBM50669031(CHEMBL6191447)
Affinity DataIC50: 0.270nMAssay Description:Inhibition of human factor IIa in Tris buffer using Boc-Asp(OBzl)-Pro-Arg-AMC as substrate preincubated for 15 mins followed by substrate addition me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCoagulation factor X(Human)
Germany.F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50669031BDBM50669031(CHEMBL6191447)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human factor Xa in Tris buffer using Boc-Ile-Glu-GlyArg-AMC as substrate preincubated for 30 mins followed by substrate addition measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProthrombin(Human)
Germany.F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50669031BDBM50669031(CHEMBL6191447)
Affinity DataIC50: 8nMAssay Description:Inhibition of human factor IIa using Boc-Val-Pro-Arg-AMC as substrate measured for 20 mins in presence of human plasma by ecarin reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCoagulation factor X(Human)
Germany.F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50669031BDBM50669031(CHEMBL6191447)
Affinity DataIC50: 20nMAssay Description:Inhibition of human factor Xa using Methoxycarbonyl-D-Nle-Gly-Arg-pNA as substrate measured for 20 mins in presence of human plasma by RVV reagent ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed