BDBM506724 2-((1R,3s,5S,6r)-3-((6- fluoroquinolin-4-yl)oxy)- bicyclo[3.1.0]hexan-6-yl)- N-(1-(trifluoromethyl)-1H- pyrazol-3-yl)propanamide::US11046649, Ex. 102

SMILES NS(=O)(=O)N1CCC2(CC1)CC2c1cccc(-c2ccccc2)n1

InChI Key InChIKey=PSJZFPQMCVRBTP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 506724   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 506724BDBM506724(US12534458, Example 3)
Affinity DataEC50:  3.00E+3nMAssay Description:mGluR5 activity was determined in a cell-based assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2026
Entry Details US Patent