BDBM506733 4-(((1R,3s,5S,6r)-6-(1-(5- chloro-1H-benzo[d]- imidazol-2-yl)ethyl)- bicyclo[3.1.0]hexan-3-yl)- oxy)-6-fluoroquinoline::US11046649, Ex. 111

SMILES NS(=O)(=O)N1CCC2(CC1)[C@@H](c1cccc(-c3cccc(C(F)(F)F)c3)c1)C2(F)F

InChI Key InChIKey=CVQRTEQBNAXDRJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 506733   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 506733BDBM506733(US12534458, Example C1)
Affinity DataEC50:  430nMAssay Description:mGluR5 activity was determined in a cell-based assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2026
Entry Details US Patent