BDBM509670 US11364246, Example 23.12::US20200361871A1, Example 23.12

SMILES CC(C)(C)NC(=O)c1cc(NC(=O)Cc2ccccc2C(F)(F)F)ccn1

InChI Key InChIKey=CZRNVAVOPVOTGE-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 509670   

TargetAnoctamin-1(Homo sapiens (Human))
Tmem16A

US Patent
LigandPNGBDBM509670(US11364246, Example 23.12 | US20200361871A1, Examp...)
Affinity DataEC50:  330nMAssay Description:Cell Culture and PreparationFisher rat thyroid (FRT) cells stably expressing human TMEM16A (TMEM16Aabc variant; Dr Luis Galietta, Insituto Giannina, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAnoctamin-1(Homo sapiens (Human))
Tmem16A

US Patent
LigandPNGBDBM509670(US11364246, Example 23.12 | US20200361871A1, Examp...)
Affinity DataEC50:  330nMAssay Description:Compound activity was quantified by measuring the increase in current upon compound addition and expressing this as a percentage increase of baseline...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent