BDBM509690 4-[2-(5-Chloro-2-hydroxyphenyl)acetamido]-N-[(1s,2s)-2-hydroxycyclohexyl] pyridine-2-carboxamide::US11364246, Example 31.3a::US20200361871A1, Example 31.3::US20200361871A1, Example 31.3a

SMILES O[C@H]1CCCC[C@@H]1NC(=O)c1cc(NC(=O)Cc2cc(Cl)ccc2O)ccn1

InChI Key InChIKey=ZZUJLBRNDLRFAK-YJBOKZPZSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 509690   

TargetAnoctamin-1(Human)
Enterprise Therapeutics

US Patent
LigandPNGBDBM509690(4-[2-(5-Chloro-2-hydroxyphenyl)acetamido]-N-[(1s,2...)
Affinity DataEC50:  210nMAssay Description:Compound activity was quantified by measuring the increase in current upon compound addition and expressing this as a percentage increase of baseline...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetAnoctamin-1(Human)
Enterprise Therapeutics

US Patent
LigandPNGBDBM509690(4-[2-(5-Chloro-2-hydroxyphenyl)acetamido]-N-[(1s,2...)
Affinity DataEC50:  550nMAssay Description:Cell Culture and PreparationFisher rat thyroid (FRT) cells stably expressing human TMEM16A (TMEM16Aabc variant; Dr Luis Galietta, Insituto Giannina, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetAnoctamin-1(Human)
Enterprise Therapeutics

US Patent
LigandPNGBDBM509690(4-[2-(5-Chloro-2-hydroxyphenyl)acetamido]-N-[(1s,2...)
Affinity DataEC50:  210nMAssay Description:Cell Culture and PreparationFisher rat thyroid (FRT) cells stably expressing human TMEM16A (TMEM16Aabc variant; Dr Luis Galietta, Insituto Giannina, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetAnoctamin-1(Human)
Enterprise Therapeutics

US Patent
LigandPNGBDBM509690(4-[2-(5-Chloro-2-hydroxyphenyl)acetamido]-N-[(1s,2...)
Affinity DataEC50:  550nMAssay Description:Compound activity was quantified by measuring the increase in current upon compound addition and expressing this as a percentage increase of baseline...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent