BDBM509723 4-[[2-(5-Chloro-2-hydroxy-phenyl)acetyl]amino]-N-(1-cyano-1,2-dimethyl-propyl)pyridine-2-carboxamide::US11364246, Example 37::US20200361871A1, Example 37

SMILES CC(C)C(C)(NC(=O)c1cc(NC(=O)Cc2cc(Cl)ccc2O)ccn1)C#N

InChI Key InChIKey=ONDXTUMYQWQGCA-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 509723   

TargetAnoctamin-1(Human)
Tmem16A

US Patent
LigandPNGBDBM509723(US20200361871A1, Example 37 | 4-[[2-(5-Chloro-2-hy...)
Affinity DataEC50:  120nMAssay Description:Cell Culture and PreparationFisher rat thyroid (FRT) cells stably expressing human TMEM16A (TMEM16Aabc variant; Dr Luis Galietta, Insituto Giannina, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetAnoctamin-1(Human)
Tmem16A

US Patent
LigandPNGBDBM509723(US20200361871A1, Example 37 | 4-[[2-(5-Chloro-2-hy...)
Affinity DataEC50:  120nMAssay Description:Compound activity was quantified by measuring the increase in current upon compound addition and expressing this as a percentage increase of baseline...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent