BDBM509763 N-(4-Fluoro-1-bicyclo[2.1.1]hexanyl)-4-[[2-(5-fluoro-2-hydroxy-phenyl)acetyl]amino] pyridine-2-carboxamide::US11364246, Example 81.4::US20200361871A1, Example 81.4

SMILES Oc1ccc(F)cc1CC(=O)Nc1ccnc(c1)C(=O)NC12CC(F)(C1)CC2

InChI Key InChIKey=VRALXWVEYHOHAK-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 509763   

TargetAnoctamin-1(Human)
Tmem16A

US Patent
LigandPNGBDBM509763(US20200361871A1, Example 81.4 | N-(4-Fluoro-1-bicy...)
Affinity DataEC50:  40nMAssay Description:Cell Culture and PreparationFisher rat thyroid (FRT) cells stably expressing human TMEM16A (TMEM16Aabc variant; Dr Luis Galietta, Insituto Giannina, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetAnoctamin-1(Human)
Tmem16A

US Patent
LigandPNGBDBM509763(US20200361871A1, Example 81.4 | N-(4-Fluoro-1-bicy...)
Affinity DataEC50:  40nMAssay Description:Compound activity was quantified by measuring the increase in current upon compound addition and expressing this as a percentage increase of baseline...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent