BDBM509776 US11364246, Example 93.3::US20200361871A1, Example 93.3

SMILES CC(C)(C)c1ccc(CC(=O)Nc2ccnc(c2)C(=O)NC2(CCOCC2)C#N)cc1O

InChI Key InChIKey=PWRDZRPWDPAOLV-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 509776   

TargetAnoctamin-1(Human)
Enterprise Therapeutics

US Patent
LigandPNGBDBM509776(US20200361871A1, Example 93.3 | US11364246, Exampl...)
Affinity DataEC50:  60nMAssay Description:Compound activity was quantified by measuring the increase in current upon compound addition and expressing this as a percentage increase of baseline...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetAnoctamin-1(Human)
Enterprise Therapeutics

US Patent
LigandPNGBDBM509776(US20200361871A1, Example 93.3 | US11364246, Exampl...)
Affinity DataEC50:  60nMAssay Description:Cell Culture and PreparationFisher rat thyroid (FRT) cells stably expressing human TMEM16A (TMEM16Aabc variant; Dr Luis Galietta, Insituto Giannina, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent